Diagnostic Tools in Clinical Practice
Dried blood spot and hair fiber, as the non-invasive biological specimens, increase the accessibility of clinical screening test in remote area, and they are relatively easy to handle and preserve with no specific conditions. As with a previous result in sitosterolemia, which is a inherited lipid metabolic disorder with accumulation of plant sterols in the blood vessel, we are eager in developing the patient-friendly
assays after clinical findings in biomarker studies to bring experimental techniques into clinical practice. In contrast, a slice of frozen tissue section provides the local levels of steroids to enhance our understanding of the pathophysiological significances as the alternative diagnostics. ccumulation and metabolic malfunction, may be elucidated by steroid signatures. such as blood, urine, frozen tissue, blood spot, saliva, and hair fiber.
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Endocr-Relat. Cancer, 2016